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Darzalex 400mg 1s, Janssen

$1,432.60 $1,265.00

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Darzalex 400mg 1s, Janssen

$1,432.60 $1,265.00

Vial per bottle:1,
Manufacturer:Janssen

Category:

Description

CompositionDaratumumab
Alternativesshow-Alternatives
Main UseMultiple Myeloma
Shipping classshow-Shipping class
Cautionshow-Caution

Medicine Overview of Darzalex 400mg 1s | 98.4 Online Pharmacy

uses 98.4 Online PharmacyUses of Darzalex 400mg 1s
Darzalex as monotherapy is indicated for the treatment of adult patients with relapsed and refractory multiple myeloma, whose prior therapy included a proteasome inhibitor and an immunomodulatory agent and who have demonstrated disease progression on the last therapy

side effects 98.4 PharmacyDarzalex 400mg 1s side effects

Common

Infusion reactions, neutropenia, thrombocytopenia, fatigue, nausea, diarrhea, constipation, vomiting, muscle spasms, arthralgia, back pain, pyrexia, chills, dizziness, insomnia, cough, dyspnea, peripheral edema, peripheral sensory neuropathy, upper respiratory tract infection.

how use 98.4 e-PharmacyHow to use Darzalex 400mg 1s
Should be administered by a healthcare professional, with immediate access to emergency equipment and appropriate medical support to manage infusion reactions if they occur.

how works 98.4 Degree PharmacyHow Darzalex 400mg 1s works
Monoclonal antibody that binds with high affinity to the CD38 molecule, which is highly expressed on the surface of multiple myeloma cells. The binding to CD38 is believed to induce rapid tumor cell death through programmed cell death, or apoptosis, and multiple immune-mediated mechanisms, including complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, and antibody-dependent cellular cytotoxicity.

More Information on Darzalex 400mg 1s | 98.4 Pharmacy Online

98.4 Pharmacy advice for Darzalex 400mg 1s

  • If infusion anaphylactic reaction or life-threatening reaction (Grade 4) occurs, institute appropriate care.
  • Severe infusion reactions reported in ~50% of all patients (most during the first infusion); may also occur with subsequent infusions.
  • Nearly all reactions occurred during infusion or within 4 hr of completing infusion.
  • Prior to the introduction of postinfusion medication in clinical trials, infusion reactions occurred up to 48 hr after infusion.
  • Severe reactions have occurred, including bronchospasm, hypoxia, dyspnea, and hypertension.
  • Signs and symptoms may include respiratory symptoms (eg, cough, wheezing, larynx, throat tightness and irritation), laryngeal edema, pulmonary edema, nasal congestion, and allergic rhinitis.
  • Less common symptoms were hypotension, headache, rash, urticaria, pruritus, nausea, vomiting, and chills.
  • Premedicate patients with antihistamines, antipyretics, and corticosteroids.
  • Frequently monitor patients during the entire infusion.
  • Permanently discontinue for life-threatening (grade 4) reactions.
  • For grade 1, 2, or 3 reactions, reduce the infusion rate when restarting the infusion.
  • To reduce the risk of delayed infusion reactions, administer oral corticosteroids to all patients the first and second day after all infusions.
  • Patients with a history of obstructive pulmonary disorders may require additional postinfusion medications to manage respiratory complications.
  • Consider prescribing short- and long-acting bronchodilators and inhaled corticosteroids for patients with obstructive pulmonary disorders.
  • May increase neutropenia or thrombocytopenia induced by background therapy; monitor CBC counts periodically during treatment; monitor patients with neutropenia for signs of infection; dose delay may be required to allow recovery of neutrophils; no dose reduction is recommended, consider supportive care with growth factors or transfusions.

Warning from 98.4 Pharmacy to Darzalex 400mg 1s

Special precautions for Darzalex 400mg 1s

alcohol 98.4 Online Pharmacy
Alcohol

There is no significant data. Please contact your doctor.

pregnancy 98.4 Pharmacy
Pregnancy

Although there have not been any studies in humans or animals with Darzalex and therefore it is not known how this medication can affect unborn babies, monoclonal antibodies such as Darzalex cross the placenta and may cause harm to an unborn baby.

lactation 98.4 e-Pharmacy
Lactation

It is not known if Darzalex crosses into human milk.

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Driving

There is no significant data. Please contact your doctor.

kidney 98.4 Pharmacy
Kidney

There is no significant data. Please contact your doctor.

liver 984degree.com
Liver

There is no significant data. Please contact your doctor.

98.4 Pharmacy’s Suggestion on missing a dose of Darzalex 400mg 1s?

If you miss an appointment to receive a dose of Darzalex, call your doctor as soon as possible to reschedule.

Disclaimer

The information of 984degree.com is for reference purpose only, and 984degree.com or 98.4 Pharmacy or 98.4 Online Pharmacy is not intended to be a replacement of professional medical advice, diagnosis, or treatment. 98.4 Pharmacy suggest to ask the advice of a physician or any qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of anything you have learned from 984degree.com (98.4 Online Pharmacy)

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